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GLP1R activation might reduce cardiovascular morbidity indirectly through reductions in glycaemia, blood pressure, inflammation, postprandial lipaemia and body weight

Guadalupe Ponciano-Rodriguez, Public Health Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

Massachusetts has had broad insurance coverage for weight-loss drugs, but that is about to change in January

Topiramate is an antiepileptic with multiple proposed mechanisms (GABA modulation, glutamate antagonism, carbonic anhydrase inhibition) that produces appetite suppression and reduces food cravings

however, it is not easy to separate these benefits from improvement in diabetes or weight loss, Ali comented