ilona maher glp 1 Olympian doesn't believe healthy eating has to mean cutting out carbs, skipping treats or following strict food rules Ilona Maher on New Podcast

10.1210/clinem/dgab828 90 XourafaG.KorbmacherM.RodenM

Any decision to initiate GLP-1 therapy should involve shared decision-making that weighs individual patient factors, comorbidities, and realistic expectations about potential cognitive benefits

Most supplements add minimal benefit when using prescription medications but may cause unnecessary expense or side effects

Notably, weight loss curves in the higher dose groups had not fully plateaued at 48 weeks, suggesting that additional weight loss might be achieved with longer treatment

Unlike semaglutide, which targets only the GLP-1 receptor, tirzepatide is a dual GIP/GLP-1 receptor agonist that targets both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

In a Phase II trial, retatrutide demonstrated a mean weight reduction of over 17.5% in adults without diabetes but with obesity or pre-obesity, marking a significant advancement in weight management therapies