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Severe or persistent vomiting, severe abdominal pain radiating to the back, or signs of dehydration require urgent medical assessment
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These medications work by mimicking naturally occurring hormones that regulate appetite, slow gastric emptying, and influence insulin secretion

doi: 10.1056/NEJMoa1901118 256 PerkovicVTuttleKRRossingPMahaffeyKWMannJFEBakrisGet al

FreeSASA: an open source C library for solvent accessible surface area calculations

Moreover, it downregulates the protein levels of cell proliferation marker PCNA, decreases cell viability and number, and upregulates the protein levels of pro-apoptotic markers [91]
