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Intriguingly, a blockade of central estrogen receptors reduces the effect of a GLP-1R analog (exendin-4) on food-motivated behavior in both sexes, indicating that estrogen may modulate the effects of GLP-1 analogs not only in females but also in males (40)

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It is not possible to guarantee the drugs are safe, but women who used them before discovering they were pregnant needn't panic, she said