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The protocol is available at The Research Question What is the scope of published evidence on the effect of using GLP1-RAs and SGLT2is in people with T2D

Bariatric surgery promoted the GLP-1 secretion Bariatric surgery, which alters gut microbiota ecology, improved obesity and T2D well (11, 162)

This combined effect on blood sugar regulation and appetite suppression has led to their growing use for weight loss

Insulin resistance can be defined as a reduced sensitivity to the action of insulin within target tissue [135]

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It needs to be administered with care though Two years ago, Chirag Shah thought the only solution to his problem was surgery