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Aids in the reduction of liver fat, beneficial for NAFLD/NASH patients

Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule

With GLP1 therapeutics entering their second wave of innovation, this is a pivotal moment for teams pushing boundaries in metabolic and neuroendocrine drug development

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