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Heart palpitations can occur during GLP-1 therapy, but understanding the mechanisms and proper monitoring helps minimize risk

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A real-world study presented at ECO 2025 shows members in Emblas digital program achieved the same weight loss as seen in semaglutide trials with significantly lower doses of the drug.

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However, DPP-4 inhibitors have not reduced the risk of major adverse cardiovascular events, possibly because potentiation of SDF-1 enhances plaque growth and instability, activates deleterious neurohormonal mechanisms, and promotes cardiac inflammation and fibrosis