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In addition to causing weight loss, participants who received semaglutide had a greater improvement on cardiometabolic risk factors, as well as a greater increase in physical function

But the interesting thing about the new study is that the researchers used a low dose of retatrutide one that was too low to cause weight loss

They have significant effects on raising blood pressure, inducing insulin resistance, increasing protein catabolism, and elevating plasma glucose

This matters because GLP-1 medications work by activating specific receptor pathways that influence appetite, blood sugar, and gastrointestinal function
