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Thirst suppression is particularly problematic considering the drugs other side effects, such as vomiting and diarrhea, which cause dehydration, Daniels added

Your clinician may recommend a GLP-1 medication for type 2 diabetes if youve already tried metformin, the most common first-line treatment

In murine pancreatic Min6-K8 cells, prevention of cytosolic glutamate production by KO of a key component of the malate-aspartate shuttle or triple KO of the vesicular glutamate transporters Slc17a6, Slc17a7, and Slc17a8 impaired GLP-1-induced insulin secretion [515]

51 Gallbladder Disease Rapid weight loss can increase the risk of cholelithiasis and cholecystitis, and was observed in major GLP-1RA trials

Rest of Asia Pacific 17.4