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Treatment strategies are individualised based on disease severity, extent, response to previous therapies, and patient preferences

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669 Although lean individuals can have insulin resistance and CMD, weight gain together with CMD exacerbates insulin resistance and leads to greater storage of fat in the intra-abdominal depot, ectopic accumulation of fat in liver and muscle cells, and heightened dysregulation of adipocytokines and systemic inflammation

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CONCLUSION This metaanalysis suggests that newer GLDs may have protective benefits against lateonset seizures and epilepsy

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Chronic migraines are a complex condition, with many possible factors behind them

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