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While effective, these treatments require monitoring due to potential side effects, especially in non-diabetic patients.This therapeutic advancement represents a revolution in the management of metabolic diseases and obesity.Despite their efficacy in managing obesity and metabolic disorders, GLP-1 and GIP receptor agonists can cause side effects, which are a common reason for therapy discontinuation

Triple-agonist peptide

The development of multi-agonists with multi-organ targets may alter the natural history of these diseases

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Retatrutide should be initiated at 2 mg subcutaneously once weekly, then escalated every 4 weeks through 4 mg, 8 mg, to a maximum maintenance dose of 12 mg w...