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In June 2024, the FDA officially approved tirzepatide for the treatment of obesity-associated OSAS, marking the first GLP-1based therapy worldwide to receive this indication (16)

Main results HbA1c, body weight, and FPG SGLT2i compared to placebo Four RCTs were included, with a total of 626 patients (304 in the SGLT2i group and 322 in the placebo group), which compared the changes in both HbA1c and body weight among patients with T2DM and low cardiovascular disease risk, from baseline to follow-up ( 2 = 0%) ( Figure 2A ) and body weight levels with low heterogeneity (MD: -1.32, 95% CI: -1.82, -0.82

The vast majority of people taking semaglutide do not develop allodynia

After you eat, your intestinal L-cells release GLP-1, which signals to your brain, pancreas, and digestive tract that food has arrived

In this story If you're starting Ozempic, Wegovy or Zepbound, you deserve better than that

These patients had been diabetic for about 2.5 years and only about 15% of patients had ever been on a medication to treat their diabetes, these were truly treatment naive patients