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However, adverse effects were not mentioned in this early report, nor was cancer progression

DNJ competitively inhibits the intestinal brush border enzyme alpha-glucosidase, slowing the hydrolysis of complex carbohydrates to monosaccharides and reducing the rate and magnitude of post-prandial glucose absorption the same mechanism as the pharmaceutical compound acarbose, but derived from a botanical source
ESC Guidelines on Diabetes, Pre-Diabetes, and Cardiovascular Diseases Developed in Collaboration With the EASD

However, this risk's relevance to humans remains uncertain and requires further investigation

Diet: Reduce dietary fat intake during the initial dose escalation phase to limit bile acid-mediated colonic secretion

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