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However, the role of GLP-1R in the pathological process of OA is unclear

The data suggest a crosstalk between AT and pancreas to fine-tune energy metabolic system or may minimize the metabolic damage during diabetes

As a non-peptide growth hormone secretagogue, MK-677 serves as a valuable research tool for investigating endocrine signaling, growth hormone physiology, muscle and bone metabolism, and age-related hormonal changes in controlled laboratory environments

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Inhibitors of DPP-4 participate in the pancreatic-endocrine-osseous axis by increasing endogenous GLP-1

May increase energy use and support fat burning
