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Considering the body weight reduction of more than 10% and the significant improvement in glycemic parameters without an increased risk of hypoglycemia, this trial establishes the efficacy and safety of the 7.2 mg dose of semaglutide compared with placebo in adults with obesity and type 2 diabetes, Lingvay and colleagues wrote.

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Lawsuits allege that Saxenda, like other GLP-1 receptor agonist drugs, has caused serious gastrointestinal injuries, severe vomiting, and increased risk of stomach paralysis

conceptualized the review structure, conducted literature review and synthesis, contributed to methodology framing, developed the first draft of the manuscript, prepared tables, and coordinated all revisions and correspondence

Understanding these effects helps set realistic expectations and guides appropriate management strategies