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Optimal A1c reduction typically takes 12 to 16 weeks at therapeutic doses

All patients must also complete a medical screening to confirm they meet the safety and eligibility criteria before starting treatment

Cardiovascular safety clinical trials with arGLP1 in patients with type 2 diabetes mellitus

Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated at least 3 years

Plasma concentration of ghrelin peaks under fasting conditions before the meal and then levels off after meal to a nadir to increase again after gastric emptying before next meal (14)

reduce dose or pause if indicated