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Participants will have 28 clinic visits and 28 phone calls with A Research Study to Compare a New Weekly Insulin, Insulin Icodec, and an Available Daily Insulin, Insulin Degludec, Both in Combination With Mealtime Insulin in People With Type 1 Diabetes (ONWARDS 6) Intervention 1 Intervention 2 Intervention 3 Not provided Anticipated Start Date Not provided Actual Start Date 2021-04-30 Anticipated Date of Last Follow-up 2025-05-27 Estimated Primary Completion Date Not provided Estimated Completion Date Not provided Actual Primary Completion Date 2022-04-28 Actual Completion Date 2022-12-02 Age Cohort Genders Accepts pregnant individuals Unspecified Accepts lactating individuals Unspecified Accepts healthy individuals No Inclusion Criteria: * Male or female aged greater than or equal to 18 years at the time of signing informed consent

Tirzepatide dual GIP/GLP-1 mechanism produces greater average weight loss (22.5% vs 15% to 17% for semaglutide in comparable trials) but also tends to cause more gastrointestinal side effects, particularly at higher doses

Compounded medications such as MIC + B12 are not FDA approved

A few of these other organ systems that interact with glucagon, insulin, and cortisol include the thyroid, reproductive system, adrenals, kidneys, liver, heart, and brain

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Our Semaglutide and Tirzepatide weight loss program in Chicago is designed to provide safe, effective, and sustainable results while supporting your overall wellness