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Some researchers report worse nausea during the luteal phase (the two weeks before menstruation), when progesterone is already causing gastrointestinal symptoms

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If you miss a dose and it's been less than 4 days (96 hours) since your scheduled injection, take it as soon as possible

This is not a formal ceiling because no FDA-approved limit exists, but it represents the upper range of what is supported by preclinical scaling and provider experience

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