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A new oral GLP-1 medication can help adults with obesity and Type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher.

Suggested Caption: On November 26, 2024, the Centers for Medicare &

Millions of people started taking GLP-1 Drugs (Semaglutide or Tirzepatide) after the trials ended and drugs reached the market

Thirteen trials involving 5,807 participants were identified

Currently, the Food and Drug Administration (FDA) has approved seven GLP-1 prescription medications:GENERIC NAMEBRAND NAMEFORMSSemaglutideOzempicRybelsusWegovyInjectionOral PillTirzepatideMounjaroZepboundInjectionLiraglutideVictozaSaxendaInjectionDulaglutideTrulicityInjectionExenatideByettaInjectionLixisenatideAdlyxinInjectionOrforglipron*Foundayo*Oral Pill*Non-peptide, small molecule When used in addition to a reduced calorie diet and increased physical activity, these medications are FDA approved for one or more of the following:Improving blood sugar levels in adults with T2D.Reducing excess body weight and keep it off long term in:Adults and children aged 12 years and older with obesity.Adults who are overweight who also have at least one weight-related medical problem (such as high blood pressure, diabetes, or high cholesterol)Reducing the risk of major adverse cardiovascular events in adults with T2D who have heart disease or are at high risk for these events.Can Service Members use GLP-1 prescription medications?GLP-1 medications are only available with a prescription from a qualified healthcare provider
