summit clinical trial tirzepatide Effects of on the Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity Tirzepatide: First Approval | Drugs
Description
Cagrilintide and the combination drug CagriSema are investigational treatments currently undergoing regulatory review

While a single 5-mg dose pharmacokinetic study cannot provide long-term data, results from phase III studies consistently showed decreases in mean alanine transaminase and aspartate transaminase values in people with T2D treated with tirzepatide (mean percent changes from baseline ranged from 12 to 33% for alanine transaminase and 1 to 16% for aspartate transaminase) [9,10,11,12,13]

pmid:34984808 39

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