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Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial

We then plotted the cumulative medication cost over time against the flat cost of each surgery, thus calculating "break-even points" (when medication costs equal surgery costs)

Reducing from 1 mg to 0.5 mg, or from 2 mg to 1 mg, is a perfectly valid approach

The most important surprise may be that the medications themselves are only part of the story

Through histologically assessing the endothelial marker CD31, we indirectly investigated the placental vascular structure and blood flow