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Tirzepatide binds 3-adrenoceptors and modulates cAMP/cGMP balance and GLUT4 translocation in cardiomyocytes independently of incretin receptor engagement

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We discuss adverse events of specific interest observed with these therapies (and their potential underlying mechanisms), including GI side effects, psychiatric, ocular, thyroid, biliary, and pancreatic complications (Table 1)
Exenatide and Metformin express their anti-inflammatory effects on human monocytes/macrophages by the Attenuation of MAPKs and NFB signaling

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