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Retrieved from Makama, M., Skouteris, H., Moran, L

doi: 10.1073/pnas.1218525110 [DOI] [PMC free article] [PubMed] [Google Scholar] 15

The Phase 2 data showing 24.2% body weight loss in 48 weeks through a novel triple-agonist mechanism is unprecedented

But unlike Novo Nordisk, which took its injectable active ingredient and made it in pill form with some tweaks, Eli Lilly is doing a whole new active ingredient

Beyond pain relief, weight loss through GLP-1 treatment can slow cartilage deterioration and reduce the need for pain medications, steroid injections, or eventual joint surgery
La Asociacin Americana de Diabetes (ADA) recomienda un enfoque centrado en el paciente para la seleccin de tratamientos, y en personas con enfermedad cardiovascular aterosclertica, alto riesgo cardiovascular, enfermedad renal crnica o insuficiencia cardaca, un GLP-1 con beneficio cardiovascular demostrado puede considerarse independientemente del uso de metformina
