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GLP-1 Reduces appetite, slows gastric emptying GIP Enhances insulin, improves fat metabolism Glucagon Increases energy expenditure, burns fat Based on Phase 2 clinical trial data (published in NEJM, 2023), retatrutide's side effects are primarily gastrointestinal, similar to other GLP-1 agonists but with some differences due to the glucagon component

Some specific instructions may include: It must be taken 2 times daily at the same time each day

It is important to note that baseline HbA 1c was 6.4% in both groups which is below the American Diabetes Association (ADA) target for good glycemic control

[Its] unclear if it had an association with decreasing breast cancer recurrence risk

Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

Spironolactone is also known as an aldosterone antagonist