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Mitigating Side Effects Several strategies have proven effective for managing adverse events: Starting with lower doses (e.g., 0.5 mg) rather than higher doses Implementing gradual dose escalation with adequate time between increases Maintaining patients at current doses longer when side effects emerge Monitoring and providing supportive care for gastrointestinal symptoms[8] These approaches can significantly improve tolerability and adherence to the medication regimen

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So, while we should always be grateful for scientific breakthroughs that ease care, we should also recognize that its the clinicians, new technology, and new care models that ultimately determine whether innovation leaves a lasting impact.

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