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Diabetes Obes Metab (2021) 23(3):75462

case series in the American Journal of Health-System Pharmacy and the allodynia incidence study published on medRxiv

Conclusion: This meta-analysis of RCTs provides reassuring evidence that GLP-1 receptor agonists were not associated with an increased risk of gastrointestinal cancers, with signals suggesting a possible reduction in colorectal and liver cancer incidence that should be interpreted cautiously

GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice

However, this evidence tends to be: a) conflicting or inconclusive

Research shows that GLP-1 receptor agonist therapy consistently reduces caloric intake, with frequent inadequacy of protein intake and occasional sarcopenia (age related muscle loss)