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Its synthesis requires advanced laboratory techniques because it must successfully bind to and activate three distinct metabolic pathways: GIP, GLP-1, and glucagon

10.1016/j.ajpath.2024.12.003 [DOI] [PubMed] [Google Scholar] Tang H., Lu Y., Okun M

[DOI] [PubMed] [Google Scholar] 55.Li ZY, Zhang N, Wen S, Zhang J, Sun XL, Fan XM, et al

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The peptide's complex three-dimensional structure remains vulnerable to environmental stressors including temperature fluctuations, moisture exposure, light degradation, and oxidative processes that can irreversibly damage the active pharmaceutical ingredient
