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Description
Glucose is transported into intestinal L-cells by sodium-glucose cotransporters, and the resultant increase in Ca 2+ influx triggers GLP-1 secretion 32

2-oleoyl glycerol (2OG) is a lipid that has been studied for its potential to help promote the release of GLP-1 in the body
Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: Single-arm, open-label, multicentre, phase 3 trials

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As for nonfatal MI, both SGLT-2 inhibitors and GLP-1RA are similar, but SGLT-2 inhibitors only are superior to DPP-4 inhibitors

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