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The most common side effect is temporary nausea during dose escalation, which usually resolves within days

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When you lose a significant amount of weight, your body undergoes hormonal adaptations designed to push you back toward your previous weight

This can be a sign of intramuscular injection

Alternatively, the guidelines recommend choosing alternative glucose lowering therapies if cost is a major issue for a patient as these brand-name medications are highly priced [38]

If a plateau coincides with being early in the ladder, the answer is usually to complete the next scheduled step as tolerated rather than jumping doses