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Inform patients about the importance of self-management practices including glucose monitoring and timing of dosing
A therapy that reduces appetite while also improving liver fat metabolism could have advantages beyond weight reduction alone

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J Cereb Blood Flow Metab 31(8):16961705 Perry T, Holloway HW, Weerasuriya A, Mouton PR, Duffy K, Mattison JA, Greig NH (2007) Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

The primary consideration is overlapping gastrointestinal side effects both medications can cause diarrhea, nausea, and stomach pain, especially during the initial weeks of treatment