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Description
Novel dual and triple agonists targeting GLP-1, GIP, Glucagon, and GDF15 for type 2 diabetes and obesity management

[DOI] [PMC free article] [PubMed] [Google Scholar] 352.Hisadome K., Reimann F., Gribble F.M., Trapp S

Clinical studies, as well as surveillance post-marketing for these drugs, showed no association between these drugs and the incidence of medullary thyroid cancer[52]

During 2024 and 2025, the GLP-1 class was increasingly defined by expanded use cases and approvals, with existing drugs gaining indications including cardiovascular risk, sleep apnea and kidney disease

Jones KL, Rigda RS, Buttfield MDM et al (2019) Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes

Semaglutide medications work by mimicking increased levels of a hormone called GLP-1 (glucagon-like peptide 1), a satiety signal that slows digestion and makes us feel full