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Diabetes Ther 10 , 12051217 (2019)
doi: 10.1074/jbc.274.7.4124

That difference can show up in daily life

PFKFB3 is a critical glycolytic enzyme that converts fructose-6-phosphate (F-6-P) into fructose-2,6-bisphosphate (F-2, 6-BP), which in turn allosterically activates 6-phosphofructo-1-kinase (PFK1)

Weight loss is never guaranteed, and individual results vary
