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The concern is aspiration, food remaining in the stomach despite fasting because the medication has slowed emptying

[DOI] [PubMed] [Google Scholar] 84.McMorrow HE, Lorch CM, Hayes NW, Fleps SW, Frydman JA, Xia JL, et al
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"Further evidence will be necessary before we can see the complete picture, but they show promise as, at the minimum, an adjunct to current therapy," says Esposito