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The fat-to-lean mass ratio improved from 0.93 at baseline to 0.70 at week 72 in the tirzepatide group, compared to 0.95 to 0.88 in the placebo group

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Patients taking GLP-1 agonists often experience reduced appetite and early satiety, which are therapeutic effects of the medication

Output files were visualized in UCSF ChimeraX volume series and captured as movies(Goddard et al

Individual variation is significant, and this combination should only be considered with guidance from a knowledgeable provider