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Critical Methodological Limitations: The authors note that the vast majority of existing trials carry a high risk of bias, were funded directly by pharmaceutical firms, and rarely enrolled participants holding a formal, standalone clinical diagnosis of BED

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The study, which was previewed in an August press release by the drugs maker and trial-runner Novo Nordisk, was published in full Saturday in the New England Journal of Medicine, timed to a presentation of the findings at the American Heart Association conference in Philadelphia

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Then, COVID hit

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