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Abbreviations: AMI: acute myocardial infarction

Accessed August 21, 2012

Alcohol- and other substance-use disorders may well benefit from the effects of GLP-1RAs on dopamine and opioid pathways that are dysregulated in addiction 243 , as seen in some of the studies we identified, and the same could also apply to other under-investigated disorders with similar underlying dysfunctions (for example, gambling disorder)

[8] Liraglutide (Saxenda) also licensed for weight management in adults meeting similar BMI thresholds

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Furthermore, access to GLP1-RAs is a major issue for uptake remaining relatively low despite the high efficacy of these medications (Rodriguez et al., 2025)