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The mature megakaryocyte is a giant cell (50 to 100 m in diameter) resulting from repeated cycles of endomitosis, which means that it undergoes repeated cycles of DNA replication without cell division, leading to polyploidy, typically up to 16N (128N can be observed)

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Given the limited published data on GLP-1 use in GDM, this platform provided the most relevant and up-to-date information, including ongoing studies with detailed protocols not yet available in peer-reviewed literature