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SCFAs mediate systemic antioxidant responses via gut-organ axis communication, while EVs ameliorate intestinal barrier dysfunction through MAPK signaling pathway modulation

To overcome this limitation, various modifications and delivery strategies to enhance the pharmacokinetic properties and therapeutic efficacy of GLP-1 analogs have been studied

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Compared with other second- or third-line glucose-lowering medications, the GLP-1RAs demonstrated a lower rate of adverse CVEs, including heart failure (HR 0.88

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