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Mechanistic Comparison# Dosing Comparison# Amycretin Dosing# Amycretin dosing is investigational: Subcutaneous: Once-weekly injection, doses up to 60 mg studied in phase 1b/2a over 36 weeks Oral: Daily tablet, doses up to 50 mg (or 2 x 50 mg) studied in phase 1 Phase 2 T2D: Both subcutaneous and oral formulations studied over 36 weeks Phase 3 dose selection will be informed by the completed phase 2 data

DiMarchi (Indiana University Bloomington, USA) for helpful discussion

When microdosing is clinically appropriate, a provider can guide it safely through Josies microdose GLP-1 options for midlife women

An understudied population Drugs like Ozempic, Wegovy and Zepbound are "glucagon-like peptide-1 receptor agonists," or GLP-1s, for short

According to the above consensus, patients without risk factors may continue their GLP-1RAs therapy in the perioperative period
