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Indeed, GLP-1 RAs and thiazolidinediones are the only two classes of diabetic drugs that have been shown to reduce stroke risk [70]

STAT News noted that the new deal stems from pricing negotiations rather than a full legislative overhaul

Physicians have years of experience managing its side effects, drug interactions, and dosing nuances. The Wegovy pill works by mimicking a protein in your body called glucagon-like peptide 1 (GLP-1)

One possible explanation is that the effect of GLP-1RAs on stroke outcomes is produced through a combination of central and peripheral mechanisms, potentially associated with weight loss and blood pressure, as albiglutide did not produce substantial weight loss or systolic blood pressure differences