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The RLS and PLMD study showed that multiple circadian rhythm-controlled genes were suppressed at night in patients, and that this circadian disruption caused increased ferroptosis in the dopaminergic neurons

Avolio, F

Appetite Cravings Impacts areas of the brain that regulate appetite, leading to reduced hunger and increased feelings of fullness

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Nevertheless, the consistency of preclinical findings has fueled optimism that GLP-1based therapies may ultimately find uses far beyond diabetes and obesity