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In more refractory cases, drugs with varied mechanisms of action (MOA) in combination are used in clinical practice (31)

Antidiabetic agents for treatment of Parkinsons disease: a meta-analysis
Mosenzon, P

Colbert recommends working with your primary care physician whenever possible so side effects and lab markers can be monitored appropriately.

These may include: Nausea Vomiting Diarrhea Constipation Bloating or gas Decreased appetite Fatigue To minimize side effects, its important to start with a lower dose and gradually increase as tolerated

Medaris, A
