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NAION risk was also higher among semaglutide users from 2021 to 2023 compared with empagliflozin using both NAION definitions

The delayed emptying effect is most pronounced during the first few hours after taking semaglutide, especially at higher doses

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Interaction between these factors contributes to the complexity of obesity and makes its treatment more challenging as the result of the complex interaction among different genes and other risk factors such as environmental and lifestyle factors (6)

DOI: 10.1128/jvi.00401-26.

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