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This prevents dose-stacking and allows your body to adjust metabolically without heightened side effects

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risk ratio 4.5, 95% CI 2.3-9.0) and testosterone deficiency (1.53% vs
10.1073/pnas.100129497 364

"A clinician may consider prescribing this medicine 'off-label' if they think it would benefit a patient with PCOS, but this would need a careful discussion with them about the benefits and potential risks," Balen said

Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat fed mice
