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1 Potential candidates for MASLD and their mechanisms of action

This is advantageous for many peptide purifications and drastically increases the possible method options

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This is especially important for peptide drugs due to their sensitivity

Expanding coverage would make these products more accessible to underserved populations, particularly those disproportionately affected by obesity and diabetes

Activation of Notch signaling and the expression of its downstream target gene, hairy and enhancer of split 1 ( Hes1 ) in TA cells repress the expression of transcription factors crucial for entry into the secretory lineage including atonal homolog 1 ( Atoh1 ) and induce absorptive cell fate commitment