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In the two trials, improvements in all prespecified cardiometabolic measures, including waist circumference, systolic and diastolic blood pressure, fasting insulin, lipid, and aspartate aminotransferase levels, were observed with tirzepatide (Jastreboff et al

Did the study have limitations

The Bottom Line Supporting your bodys natural GLP-1 production doesnt require drastic changes or prescription meds

Emphasis is placed on secretion and action of GIP, GLP-1, and GLP-2 as part of the gut-bone axis

This hypothesis was supported by the Gorelik study which found no benefit in non-obese patients 92 whilst a smaller study by Anderson et al

Patients should be counselled that if they develop symptoms of pancreatitis they should consult a health professional for assessment
