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If you have concerns about alcohol consumption, inform your PlexusDx provider, who can assess your full health picture and refer you to addiction specialists if needed

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When consulting your healthcare provider, note the duration, frequency, and specific characteristics of stool changes, along with any accompanying symptoms such as pain, nausea, or appetite changes

Clinical implication Clinicians are encouraged to perform comprehensive evaluations prior to prescribing GLP-1 RA therapy in patients with a history of pancreatic disorders or other pancreatitis risk factors

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The injectable obesity medications Semaglutide 2.4 mg, a selective GLP-1 receptor agonist, produces robust and durable weight loss of approximately 1516% over 68 weeks ( Tirzepatide, a dual gastric inhibitory polypeptide (GIP)/GLP-1 receptor agonist, delivers even greater weight loss, exceeding 20% at the highest dose in pivotal trials ( Retatrutide, a triple agonist targeting GIP, GLP-1, and glucagon receptors, represents a further step in efficacy, with 24.2% weight loss achieved within 48 weeks in phase 2 studies ( Survodutide, an oxyntomodulin analogue, achieved clinically meaningful weight loss ( Table 2