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Under stress conditions, BiP is released and thus activates the IRE-1, ATF6, and PERK signaling cascades

2022;36 doi: 10.47176/mjiri.36.39

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The company will now formally push forward with seeking approval from the FDA and other regulatory agencies

the most common adverse effects were gastrointestinal, dose-related, mildmoderate, and reduced in part by a lower starting dose (2 mg vs

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