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When we finish a task or accomplish a goal, our brain releases dopamine that gives us a feeling of euphoria

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GIP is produced and secreted into the blood by K cells located in the mucosa of the upper gastrointestinal tract's duodenum and upper jejunum while GLP1 is produced and secreted into the blood by L cells located in the mucosa of the lower gastrointestinal tracts small and large intestines

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doi: 10.1016/j.cmet.2016.06.021 42 FinanBClemmensenCZhuZStemmerKGauthierKMullerLet al

ASM cells were transfected with pcDNA301-GLP-1R or GLP-1R siRNA