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Latest study showing efficacy of nonpeptide oral GLP-1R agonists currently under development

Furthermore, several novel therapeutic compounds (GIP receptor antagonists and agonists including multiple-targeting compounds) have also shown beneficial glucometabolic and body weight lowering effects in individuals with type 2 diabetes and obesity (40, 41)

Original research and review articles published within the last ten years were included in the study, while manuscripts without available full text were excluded

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More than 54.6% of participants achieved 10% weight loss, alongside meaningful improvements in cardiometabolic markers, including blood pressure, waist circumference, and lipid levels